February 6, 2023

MUI Daily News

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Kidney was successfully transplanted from pig to human, which is the first of its kind in the world

The organ of the animal was genetically modified so that it could not be rejected by the human body.

Scientists in the United States have succeeded in making a genetically modified pig’s kidney work for humans, a breakthrough that reflects the hopes of many waiting for transplant surgery. If success is guaranteed, we can really imagine that pigs could one day be raised to provide the organs (lungs, hearts, etc.) that humans need. More than 100,000 Americans are currently on the waiting list for organ transplant surgery. 17 people die every day while waiting for donations.

He underwent surgery at NYU Langone Hospital in New York on September 25, and the organ was not discarded by the human body using the genetically modified pig’s kidney. The kidney was not strictly fitted into the human body, but the brain was attached to the dead patient’s blood vessels, allowing his family to experiment at the upper level of his leg. Kidney “I did a good job” Within two and a half days of the trial, Robert Montgomery, director of the NYU Langone Institute of Transplantation, told AFP. “He did what he had to do. He produced urine.”

“No quick rejection”

Such transplant surgery has already been tried in animals, but not yet in humans. This is because there are antibodies that attack a type of sugar that is common in the human body “In all pig cells”, Cause “Immediate rejection” Element, explains Robert Montgomery. But this time the animal was genetically modified and no longer produced this sugar “Rapid Kidney Rejection” Found.

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Since the detailed results of the study have not yet been published in the journal Science, some experts have welcomed the news with caution. “However, this is an interesting step on the road to using genetically modified pigs as a source for transplantation.”, Commented Alan Archibald, a geneticist at the University of Edinburgh. Genocrafts – from animal to human – are not new. Physicians have been trying cross-breeding transplants since the 17th century, and early experiments focused on animals.